The CBSE Class 12 Biology Compartment Exam 2025 was conducted on 15 July (Tuesday) for 2.5 hours from 10:30 AM to 1:00 PM. CBSE Class 12th Compartment Question Paper 2025 for Biology along with the solution pdf is available here.
The theory paper carries a total of 80 marks, and the internal assessment is for 20 marks, making the exam total out of 100 marks. The exam included key topics like Reproduction, Genetics and Evolution, Human Health and Disease, Biotechnology, Ecology, and Environment, which required a strong conceptual understanding and a thorough grasp of biological processes and terminology.
Also Check: CBSE Class 12 2025 Question Papers With Solution Pdf
CBSE Class 12 Biology Compartment Question Paper 2025
CBSE Biology Compartment Question Paper 2025 | Download PDF | Check Solution |

Long ribbon-like pollen grains are seen in some:
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Estrogen is secreted by:
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Amniocentesis is a technique that is used to:
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In humans, non-disjunction of the 21st pair of chromosomes leads to:
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Which one of the following codons has dual function?
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Which one of the following options gives the correct temperature condition and the mixture of the gaseous components that were used by S.L. Miller in 1953 to prove abiogenesis of life?
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The mosquito-borne disease in humans causing chronic inflammation of the lymphatic vessels is:
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In plants, which one of the following helps in the absorption of phosphorus from soil?
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The most primitive ancestor of humans is:
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The sequence that controls the copy number of linked DNA in the vector is termed:
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Crystals of Bt toxin produced by some bacteria do not kill the bacteria producing them because:
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The population interaction where one species is harmed and the other is unaffected is:
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Assertion (A): Periodic abstinence is a method in which couples avoid coitus from day 10 to 17 of menstrual cycle.
Reason (R): Periodic abstinence has limited effectiveness because menstrual cycles are not always regular.
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Assertion (A): \textit{Streptococcus pneumoniae and \textit{Haemophilus influenzae are responsible for causing infectious diseases in human beings.
Reason (R): A healthy person acquires the infection by inhaling the droplets/aerosols released by an infected person.
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Assertion (A): Biotechnology produces transgenic micro-organisms that act as microfactories for proteins.
Reason (R): To produce proteins for human use like insulin, transgenic microorganisms can be developed.
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Assertion (A): Gross primary productivity is always less than net primary productivity.
Reason (R): Rate of synthesis of organic matter by consumers is known as secondary productivity.
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The mosquito-borne disease in humans causing chronic inflammation of the lymphatic vessels is:
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In which of the following plants are both male and female flowers born on the same plant and the mode of pollination can be geitonogamy or xenogamy?
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Which one of the following hormones is secreted by the human placenta that helps in the maintenance of pregnancy?
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The periodic abstinence by a couple for family planning should be from:
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Select the \textit{incorrect match from the following:
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You know that there are twenty different types of naturally occurring amino acids and four different types of bases in the DNA. A combination of 3 such bases code for a specific amino acid. If instead there are 96 different amino acids and 12 different bases in the DNA, then the minimum number of combination of bases required to form a codon is:
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The type of bond represented by the dotted line ‘------’ in a schematic polynucleotide chain is:
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In which of the following conditions/diseases is there a substantial increase in the activity of mast cells observed in the human body?
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\textit{Lactobacillus that sets milk into curd is categorised as:
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Which one of the following transgenic animals is being used to test the safety of the polio vaccine?
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Restriction Endonuclease – Hind II always cuts DNA molecules at a particular point by recognising a specific sequence of:
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Which scientist proposed that "embryo never pass through the adult stages of other animals"?
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The flows of genetic information in central dogma are in which direction?
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Which scientist proposed that “embryo never pass through the adult stages of other animals”?
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They are useful to get rid of aphids.
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What is the correct name of AI technique in assisted reproductive technologies?
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Genes which control \(\alpha\)-Thalassemia and \(\beta\)-Thalassemia are present on which number of chromosomes?
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Distance between two consecutive base pairs of DNA is \rule{2cm{0.1mm
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In a family tree of dinosaurs, which dinosaur was about 20 feet in height \& had huge fearsome dagger-like teeth?
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If a person is positive in Widal test, then that person is infected by which pathogen?
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Which chemical is obtained from microorganism \textit{Aspergillus niger?
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The first r-DNA was constructed in which microorganism?
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Who proposed the competitive exclusion principle?
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How many billion tons productivity of oceans?
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How many number of biodiversity hotspots in the world right now?
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Assertion (A): Apple is false fruit.
Reason (R): Thalamus also contributes to fruit formation in apple.
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Which one is not determined in the developing foetus by using amniocentesis?
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If a colour-blind woman marries a person whose mother is colour-blind, then what is the probability of colour blindness in their offspring?
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Difficulty Level of CBSE Compartment Exam 2025 (Expected)
The CBSE Class 12 Compartment Exam 2025 is expected to be a bit easier than the 2024 exam. Most questions will probably be from key concepts and can be easier to understand and solve.
Aspet | Compartment Exam 2024 | Compartment Exam 2025 (Expected) |
Overall Difficulty Level | Moderate | Moderate to Slightly Easy |
1-mark & 2-mark Questions | Mostly Easy and Direct | Expected to be Easy and Concept-Based |
3-mark Questions | Mixed – Some were straightforward, some tricky | Expected to be Conceptual but Manageable |
4-mark Questions | Slightly Challenging, Required Deeper Understanding | May Include Application-Based but Familiar Questions |
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