General Physiology and Biochemistry is the block most BDS graduates leave until last, and then lose easy marks on. The questions are predictable once you know which tables the examiner keeps coming back to. On this page you get free NEET MDS General Physiology and Biochemistry sample papers built to the latest NBEMS pattern, each with worked solutions so you can rebuild the vitamins, enzymes and acid base work you last touched in first year.
Official website: natboard.edu.in
NEET MDS General Physiology and Biochemistry Sample Papers 2027
NEET MDS General Physiology and Biochemistry Sample Paper 1
NEET MDS General Physiology and Biochemistry Sample Paper 2
NEET MDS General Physiology and Biochemistry Sample Paper 3
NEET MDS General Physiology and Biochemistry Sample Paper 4
NEET MDS General Physiology and Biochemistry Sample Paper 5
NEET MDS General Physiology and Biochemistry Sample Paper 6
NEET MDS General Physiology and Biochemistry Sample Paper 7
NEET MDS General Physiology and Biochemistry Sample Paper 8
NEET MDS General Physiology and Biochemistry Sample Paper 9
NEET MDS General Physiology and Biochemistry Sample Paper 10
Download any of the NEET MDS General Physiology and Biochemistry sample papers above and solve it in one timed sitting of about 11 minutes, which is the exact share this subject gets in the real exam. Each paper carries 14 single best response questions worth 56 marks, and every question comes with a full explanation so you can see the reasoning rather than just the answer.
You can download these papers here on Collegedunia, and you should also check the official website natboard.edu.in for the information bulletin and the exam date before you plan your practice.
- NEET MDS General Physiology and Biochemistry Sample Papers 2027
- NEET MDS General Physiology and Biochemistry Exam Pattern and Marks Distribution 2027
- NEET MDS Physiology and Biochemistry Sample Papers - Why Recent Papers Matter Most
- NEET MDS Physiology and Biochemistry Chapter Wise Weightage - High Scoring Topics to Focus in Sample Papers
- NEET MDS Physiology and Biochemistry Sample Paper Video Solutions 2027 - Watch Before You Start Solving
- How to Use NEET MDS Physiology and Biochemistry Sample Papers to Clear in First Attempt
- NEET MDS Physiology and Biochemistry Textbook vs PYQ Balance
- NEET MDS Physiology and Biochemistry 4 Week Preparation Plan Using Sample Papers
- FAQs on NEET MDS General Physiology and Biochemistry Sample Papers 2027
- Subject questions: 14 questions from General Physiology and Biochemistry, worth 56 marks at 4 marks each.
- Time budget: The full paper allows 180 minutes for 240 questions, which works out to 0.75 minutes per question, so this subject deserves about 11 minutes.
- Marking scheme: +4 for a correct answer and -1 for a wrong one. Unattempted questions carry no penalty.
- Paper format: 240 single best response questions worth 960 marks, split into a time bound Part A of 100 questions in 75 minutes and Part B of 140 questions in 105 minutes.
- Mode: Computer based test conducted by NBEMS, in English only.
- Syllabus base: Your BDS first year physiology and biochemistry, with vitamins, enzymes and acid base balance carrying most of the weight.
- Past papers: NBEMS does not release NEET MDS question papers, so pattern matched sample papers are the closest practice you can get.

NEET MDS General Physiology and Biochemistry Exam Pattern and Marks Distribution 2027
Physiology and Biochemistry are counted together as one basic subject in NEET MDS. Their 14 questions sit inside Part A with the other pre-clinical subjects, so the pattern below tells you the pace you need around them.
- Total paper: 240 single best response questions worth 960 marks in 180 minutes.
- Part structure: Part A holds 100 questions in 75 minutes and Part B holds 140 questions in 105 minutes. The parts are time bound, so once Part A closes you cannot return to it.
- Physiology and Biochemistry share: 14 questions worth 56 marks, which is close to 6 percent of the paper.
- Marking: +4 for correct, -1 for wrong, 0 for unattempted. A wrong answer costs you 5 marks against a correct one.
- Question style: Single best response. Mostly direct recall of values, pathways and deficiency states, with a few applied clinical stems.
- Conducting body: NBEMS, on the official website natboard.edu.in.
Key advice: This subject is full of numbers, and numbers are either known or not. You get 45 seconds per question in Part A, so if a value has not come to you within about 20 seconds it is not coming. Mark it and move on.
NEET MDS Physiology and Biochemistry Sample Papers - Why Recent Papers Matter Most
NBEMS has never released a NEET MDS question paper, so anything sold to you as an official past paper is a student recall. Recalls degrade as they get copied, and biochemistry recalls degrade fastest because a single wrong digit in a value turns a useful fact into a memorised error. Papers written to the current pattern are safer practice.
- Reference values get revised: Vitamin requirements and lab ranges do get updated. An old recall may be teaching you a number the examiner no longer accepts.
- The pace changed: At 240 questions in 180 minutes, this exam rewards instant recall. Practice sets built for a slower pattern train you to sit and think, which you cannot afford here.
- The core barely moves: Vitamins, enzyme kinetics and acid base balance come back year after year. Recent papers keep those in proportion rather than drifting into research trivia.
NEET MDS Physiology and Biochemistry Chapter Wise Weightage - High Scoring Topics to Focus in Sample Papers
The 14 questions are weighted towards the areas that connect to dentistry and to clinical medicine. Vitamins and enzymes carry the most, partly because they are easy to frame as single best response questions. The table below shows how our sample papers distribute them.
| Chapter | Questions | Difficulty | What to Watch For |
|---|---|---|---|
| Vitamins and Minerals | 2 | Easy to Moderate | Deficiency states and coenzyme forms. Vitamin D, C and the B group repeat the most. Pure recall marks. |
| Enzymes and Enzyme Kinetics | 2 | Moderate | Km and Vmax, and the difference between competitive and non-competitive inhibition. Learn what each does to Km. |
| Metabolism of Carbohydrate, Lipid and Protein | 3 | Moderate to Hard | Rate limiting enzymes and ATP yields. Glycolysis and the urea cycle are the usual sources. |
| Acid Base Balance and Body Fluids | 2 | Moderate | The four disturbances and compensation. Read the pH first, then the bicarbonate, then decide. |
| Blood and Haemostasis | 2 | Moderate | The coagulation cascade and bleeding time versus clotting time. This links straight to extraction questions. |
| Nerve, Muscle and Endocrine Physiology | 3 | Moderate | The action potential, neuromuscular transmission, and calcium regulation by PTH, calcitonin and vitamin D. |
Note: Do not treat vitamins as beneath you because they are easy. Those 8 marks take one evening to lock down, while three marks of metabolism might cost you a week and still not stick.
NEET MDS Physiology and Biochemistry Sample Paper Video Solutions 2027 - Watch Before You Start Solving
Biochemistry looks enormous when you open a textbook and small when you see what NEET MDS actually asks. Watching questions first is the fastest way to calibrate that gap, so you revise at the depth the exam wants rather than the depth your first year professor wanted.
The walkthrough below runs through the biochemistry questions that repeat most in NEET MDS. Watch it once, then start on Sample Paper 1 and see how many of the same patterns you recognise.
Watch:
Source: Rapid Rewind session on the top repeated biochemistry questions for NEET MDS, covering vitamins, enzymes and metabolism (YouTube)
How to Use NEET MDS Physiology and Biochemistry Sample Papers to Clear in First Attempt
This subject rewards a specific kind of revision. You are not building understanding from scratch, you are making a set of tables and values retrievable in under 20 seconds.
- Time every paper at 11 minutes. Solving 14 questions in 25 minutes proves nothing, because the real exam gives you 45 seconds each.
- Keep a values sheet. Every number you get wrong goes on one page. Read that page, not the textbook, in your last week.
- Fix pathways as whole diagrams. If you miss a rate limiting enzyme, redraw the pathway rather than memorising the single enzyme in isolation.
- Mark your guesses. Put a dot beside anything you were unsure of, then count how many dots became -1. That ratio tells you when to guess and when to leave.
- Read the solution even when correct. The explanation usually names the option you almost picked, and that is the one waiting to catch you next time.
- Track score by chapter. A steady 9 out of 14 can hide the fact that every miss is metabolism.
NEET MDS Physiology and Biochemistry Textbook vs PYQ Balance
The usual question is whether to reopen Guyton and Harper or stay with question banks. For 14 questions the honest answer is that questions lead and the textbook is a lookup tool you open when a question exposes a gap.
- Questions first, textbook second. Solve a paper, then read only what you missed. Reading Harper end to end for 14 questions is not a trade worth making.
- Keep one source for the tables. Vitamins, coenzymes and rate limiting enzymes should live in one place in your memory, not three conflicting ones.
- Skip the research depth. NEET MDS does not ask experimental detail or pathway minutiae. It asks what a well prepared final year student should know.
- Check circulating recalls. Since NBEMS releases nothing, treat any recalled value as unverified until an explanation you trust backs it up.
NEET MDS Physiology and Biochemistry 4 Week Preparation Plan Using Sample Papers
- Week 1: Revise vitamins, minerals and enzymes including Km, Vmax and the inhibition types. Solve Sample Papers 1 and 2 at 11 minutes each and start your values sheet.
- Week 2: Work through carbohydrate, lipid and protein metabolism, focusing on rate limiting enzymes and ATP yields. Solve Sample Papers 3, 4 and 5, redrawing any pathway you got wrong.
- Week 3: Cover acid base balance, body fluids, blood and haemostasis. Solve Sample Papers 6, 7 and 8, and begin recording your guess to error ratio.
- Week 4: Revise nerve, muscle and endocrine physiology, then solve Sample Papers 9 and 10 back to back to test your speed. Keep the last 2 days for your values sheet only, nothing new.
FAQs on NEET MDS General Physiology and Biochemistry Sample Papers 2027
Ques.How many questions come from General Physiology and Biochemistry in NEET MDS 2027?
Ans.Physiology and Biochemistry are counted together as one basic subject carrying 14 questions worth 56 marks, out of the full paper of 240 questions and 960 marks. That is close to 6 percent of the exam, and the questions sit inside the time bound Part A rather than in a separate labelled section.
Ques.Are these NEET MDS Physiology and Biochemistry sample papers real previous year question papers?
Ans.No, and no genuine ones exist. NBEMS has never released a NEET MDS question paper, so everything circulating as a past paper is a student recall. These are original questions written to the current pattern, with 14 questions in 11 minutes and +4 and -1 marking, which is the closest practice available to you.
Ques.Which Physiology and Biochemistry topics are most repeated in NEET MDS?
Ans.Vitamins and their deficiency states come first, because they are easy to frame as single best response questions. Enzyme kinetics, particularly the effect of competitive and non-competitive inhibitors on Km and Vmax, is second. Acid base balance is the third reliable block. Together these account for roughly 6 of the 14 questions in our sample papers.
Ques.How much time should I spend on this subject in the real exam?
Ans.About 11 minutes in total. The paper gives 180 minutes for 240 questions, which is 45 seconds per question, so 14 questions work out to roughly 11 minutes. Because most of these are recall based, you should aim to finish faster and bank the saved time for the clinical subjects waiting in Part B.
Ques.Is biochemistry worth studying for NEET MDS, or should I skip it?
Ans.Do not skip it. Physiology and Biochemistry together are 56 marks, and a large part of that is recall you can secure in a few evenings. Skipping the subject also means giving up the vitamin and enzyme questions, which are among the cheapest marks in the whole paper. What you can safely skip is the deep experimental detail, since the exam does not go there.
Ques.Should I guess questions I am unsure about in this subject?
Ans.Only once you can eliminate two of the four options. With +4 for correct and -1 for wrong, a blind guess across four options roughly breaks even and adds risk for no real gain. After two options are gone the odds move clearly in your favour. Use the sample papers to learn how often your instinct is actually right before you rely on it in the exam.








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