Goiter: Definition, Causes, Symptoms, Diagnosis & Treatment

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Jasmine Grover Content Strategy Manager

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Goiter is a disease caused due to deficiency of certain vital macronutrients in the human body such as vitamins, minerals, etc. Goiter disease means an enlarged thyroid in humans which leads to either too much or too little generation of hormones. In this article, we will be looking into the various types of Goiter disease and learn about its causes, symptoms, and treatment options.

Goiter causes two conditions which are Hyperthyroidism and hypothyroidism. 

  • In Hyperthyroidism, the hormones are overly secreted. 
  • In Hypothyroidism the hormones are under secreted.

Check out Chemical Coordination and Integration. (Goiter.pdf)

Types of Goiter

There are a few different types of goiter that can happen to a person. These may also depend upon the cause of the disease. Therefore, the various types of goiter are: 

  • Colloid Goiter (Endemic): This condition occurs when there is a deficiency of iodine in the body.
  • Non-Toxic Goiter (Sporadic): The cause of this condition is still unknown but studies indicate it may be due to intake of Lithium.
  • Toxic Goiter (Nodular or Multinodular): The condition causes hyperthyroidism by forming one or more nodes that produce their own hormones.

Causes of Goiter

Goiter is caused by the deficiency of macronutrients and minerals in the body. The most common deficiency which causes thyroid is iodine deficiency. The thyroid gland requires iodine to function normally and when this is not available, the gland enlarges and tries to produce the hormones required.

The other causes are:

  • Inflammation:  When the gland suffers an inflammation, a condition known as thyroiditis is caused. This causes Goiter.
  • Graves’ Disease: This is due to the overproduction of hormones also known as hyperthyroidism.
  • Hashimoto’s Disease: This is due to the overproduction of hormones also known as hypothyroidism.
  • Nodules: These are cysts that grow on the thyroid gland causing it to enlarge. Nodules are non-cancerous.
  • Thyroid Cancer: Cancerous cells on the thyroid can also cause Goiter
  • Pregnancy: In some cases, pregnancy leads to enlargement of the thyroid gland and causes Goiter.

Symptoms of Goiter

The symptoms of Goiter are listed below:

  • Enlargement of the thyroid gland just below Adam’s apple in the neck area is the most common symptom.
  • Tightness in the neck area
  • Scratchy and Hoarse voice
  • Dizziness

Other less common symptoms include difficulty in breathing, coughing, wheezing, pain in swallowing, tiredness, dry skin, constipation, menstrual irregularities, and weight gain.

Diagnosis of Goiter

Doctors are able to diagnose thyroid goiters by examining the neck of a patient by observing whether it is enlarged or not. To confirm the diagnosis, however, the doctor may prescribe some tests which will include ultrasound, blood tests ( thyroid hormones), and a radioactive scan

Treatment of Thyroid Goiter

The treatment of Thyroid mainly depends on the type of goiter. For instance, if it is caused by Hashimoto’s thyroiditis, patients are required to take a daily medication meant for thyroid hormone replacement. One should intake radioactive iodine or medication viz. a treatment that helps in decreasing the size of the goiter, in the case of Graves disease.

Things to Remember

  • Goiter is a disease caused in the human body which causes the thyroid gland to enlarge in the front and side areas of the neck.
  • Goiter causes two conditions which are Hyperthyroidism and hypothyroidism
  • There are a few different types of goiter that can happen to a person such as Colloid Goiter, Non-Toxic Goiter, and Toxic Goiter.
  • Goiter is caused by the deficiency of macronutrients and minerals in the body. 
  • The most common deficiency which causes thyroid is iodine deficiency.
  • Doctors are able to diagnose thyroid goiters by examining the neck of a patient and through some tests.
  • The treatment of Thyroid mainly depends on the type of goiter.

Sample Questions

Ques. What is a goiter? 2 marks 

Ans. Goiter is a disease caused in the human body which causes the thyroid gland to enlarge in the front and side areas of the neck. It is caused due to a deficiency of certain vital macronutrients in the human body such as vitamins, minerals, etc.

Ques. What are the symptoms of goiter? 3 marks 

Ans. The symptoms of Goiter are listed below:

  • Tightness in the neck area
  • Scratchy and Hoarse voice
  • Enlargement of the thyroid gland
  • Dizziness

Ques. What are the types of goiter? 3 marks

Ans. The various types of goiter are: 

  • Colloid Goiter (Endemic): Due to deficiency of iodine in the body.
  • Non-Toxic Goiter (Sporadic): This might be due to the intake of Lithium.
  • Toxic Goiter (Nodular or Multinodular): Causes hyperthyroidism by forming more nodes.

Ques. How is Goiter diagnosed? 5 marks 

Ans: Several tests may help in the diagnosis. A standard procedure for the diagnosis of the Goiter includes:

  1. Physical Examination of the neck. Observing the area for signs of tenderness or nodules.
  2. Blood test to measure the levels of hormones by thyroid.
  3. Blood Test that identifies specific antibodies that are generally produced by various goiter types.
  4. Ultrasound
  5. Injecting radioactive materials in a vein for scanning or imaging thyroid.
  6. MRI or CT Scan to measure the spread and the size of goiters.

Ques. What are some of the treatments available? 5 marks 

Ans. Treatment depends upon the growth, causes, and symptoms. Conventional treatments available for goiter include the following:

  1. Observing if the goiter is small, won’t bother you.
  2. Medications for treating hyperthyroidism or hypothyroidism, as per the cause
  3. Treatment through the administration of radioactive iodine orally. It kills the thyroid cells, thereby shrinking the gland.
  4. Biopsy for the removal of the cells or tissue for a study if large nodules are present in the thyroid gland.
  5. Surgery, if the size of the goiter is causing swallowing issues or breathing difficulties.

CBSE CLASS XII Related Questions

  • 1.

    Answer the following questions:

    [(i)] Explain the structure of a mature embryo sac of a typical flowering plant.

    [(ii)] How is triple fusion achieved in these plants?

    OR

    [(i)] Describe the changes in the ovary and the uterus as induced by the changes in the level of pituitary and ovarian hormones during menstrual cycle in a human female.


      • 2.
        Student to attempt either option (A) or (B):
        (A)
        Why are restrictions imposed on MTP in India? Up to how many weeks or trimesters is MTP considered relatively safe for a female, if necessary to perform, by a medical practitioner?
        OR
        (B) Expand PID. Name any two common viral infections transmitted through sexual contact in human females.


          • 3.

            Flowering plants with hermaphrodite flowers have developed many reproductive strategies to ensure cross-pollination. Study the given outbreeding devices adopted by certain flowering plants and answer the questions that follow.

            Note : All plants belong to the same species. No pollen tube growth/inhibition of pollen germination on stigma. Pollen germination on stigma.

            • [(a)] Name and define the outbreeding device described in the above table.
            • [(b)] Explain what would have been the disadvantage to the plant in the absence of the given strategy.


              • 4.

                Answer the following questions with respect to the sex determining mechanism observed in honey bee.

                • [(a)] Name the type of sex determination system observed in honey bee.
                • [(b)] Fill in the blanks (i), (ii) and (iii) in the given question.

                • [(c)] What will be the sex and chromosome number of the progeny formed from the unfertilised eggs of honey bee?


                  • 5.

                    Use the given information to select the amino acid attached to the 3′ end of tRNA during the process of translation, if the coding strand of the structural gene being transcribed has the nucleotide sequence TAC.
                     

                      • Isoleucine
                      • Methionine
                      • Tyrosine
                      • Valine

                    • 6.

                      Study the given below single strand of deoxyribonucleic acid depicted in the form of a “stick” diagram with 5′ – 3′ end directionality, sugars as vertical lines and bases as single letter abbreviations and answer the questions that follow.

                      Name the covalent bonds depicted as (a) and (b) in the form of slanting lines in the diagram.
                      How many purines are present in the given “stick” diagram?
                      Draw the chemical structure of the given polynucleotide chain of DNA.

                        CBSE CLASS XII Previous Year Papers

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