NEET SS 2025 Question Paper (Available) - Download NEET SS Question Paper with Solution PDF

Which of the following is the most sensitive marker for myocardial infarction in the first 6 hours after symptom onset?

• (A) CK-MB
• (B) Troponin I
• (C) Myoglobin
• (D) LDH

Which of the following is the gold standard investigation for diagnosing multiple sclerosis?

• (A) CT scan of the brain
• (B) MRI with gadolinium
• (C) Lumbar puncture
• (D) EEG

Which of the following is the most common genetic mutation associated with hereditary non-polyposis colorectal cancer (HNPCC)?

• (A) APC gene mutation
• (B) MLH1/MSH2 mutation
• (C) KRAS mutation
• (D) TP53 mutation

Which of the following is the first-line treatment for acute variceal bleeding in cirrhosis?

• (A) Propranolol
• (B) Endoscopic band ligation
• (C) Octreotide infusion
• (D) Transjugular intrahepatic portosystemic shunt (TIPS)

Which of the following is the most common cause of chronic kidney disease in adults worldwide?

• (A) Diabetic nephropathy
• (B) Hypertensive nephropathy
• (C) Glomerulonephritis
• (D) Polycystic kidney disease

Which of the following is the earliest rising cardiac biomarker after myocardial infarction?

• (A) CK-MB
• (B) Troponin I
• (C) Myoglobin
• (D) LDH

Which of the following is considered the gold standard for the diagnosis of multiple sclerosis?

• (A) CT scan of the brain
• (B) MRI of the brain and spinal cord
• (C) Lumbar puncture for oligoclonal bands
• (D) Visual evoked potentials

Which of the following genes is most commonly mutated in Lynch syndrome (hereditary non-polyposis colorectal cancer)?

• (A) APC
• (B) MLH1
• (C) KRAS
• (D) TP53

Which of the following is the initial pharmacologic therapy for acute esophageal variceal bleeding in cirrhosis?

• (A) Propranolol
• (B) Endoscopic variceal ligation
• (C) Vasoactive drugs like terlipressin or octreotide
• (D) Balloon tamponade

Which of the following is the leading cause of chronic kidney disease worldwide?

• (A) Glomerulonephritis
• (B) Hypertension
• (C) Diabetes mellitus
• (D) Polycystic kidney disease

Which of the following cardiac biomarkers rises earliest after the onset of acute myocardial infarction?

• (A) Creatine kinase-MB (CK-MB)
• (B) Cardiac troponin T
• (C) Myoglobin
• (D) Lactate dehydrogenase (LDH)

According to the latest diagnostic criteria, what is the gold standard for diagnosing multiple sclerosis?

• (A) Clinical history and examination alone
• (B) Application of the 2024 revised McDonald criteria
• (C) Presence of oligoclonal bands in CSF
• (D) Evoked potentials

Which gene is most commonly mutated in Lynch syndrome (hereditary non-polyposis colorectal cancer)?

• (A) APC
• (B) MLH1
• (C) KRAS
• (D) BRAF

What is the initial pharmacologic management for suspected acute esophageal variceal bleeding?

• (A) Non-selective beta-blockers alone
• (B) Proton pump inhibitors
• (C) Vasoactive agents (e.g., octreotide or terlipressin)
• (D) Urgent beta-blocker prophylaxis

What is the leading cause of chronic kidney disease worldwide as per recent global burden studies?

• (A) Hypertension
• (B) Glomerulonephritis
• (C) Diabetes mellitus
• (D) Obstructive nephropathy